Secondary analysis.

Pretty much all risk-benefit conversations prior to radiation include a “very small risk of a second cancer” tidbit at the end. While the risk in most cases is, indeed, very small, it’s less small the higher the post-cancer life expectancy and number of radiosensitive organs in the field. This retrospective look at over 150K men receiving treatment for prostate cancer at the VA reports the rate of a potentially in-field second primary cancer more than 1 year after prostate cancer treatment was significantly higher among the roughly one-third of men receiving radiation (3.7%) than among the remaining two-thirds who didn’t receive radiation (2.5%)—details of radiation doses and volumes not available. These relevant second cancers were: bladder (1.8% v 1.4%), leukemia (0.7% v 0.5%), lymphoma (0.4% v 0.3%), rectal (0.4% v 0.3%), anogenital (0.2% v 0.08%), soft tissue (0.1% v 0.1%), and bone 0.02% v 0.01%). As expected, the separation in risk really began to diverge ten years after treatment, making this most relevant to younger men. Perhaps most paramount to clinical decision-making? Whether or not to electively treat lymph nodes. | Bagshaw, JAMA Netw Open 2022

Comments

  1. He made a lot of good changes on my credit report by erasing all the past eviction, bad collections and DUI off my credit report history and also increased my FICO score above 876 across my three credit bureaus report you can contact him for all kind of hacks . Email him here ethicalhackers009@gmail.com for more details,Whatsapp No:+14106350697 if you want to chat them up,One thing i can assure you would not regret this at all he is 100% legit.

    ReplyDelete

Post a Comment

Popular Posts