This might hurt.
This model used data from >400 patients with >600 spine mets receiving SBRT to predict the risk of pain flare. Overall, 20% of patients experienced pain flare. Five factors were associated with pain flare: RCC histology, soft tissue extension, Bilsky >0, SINS>6, and GTV >8cc. In the prediction model, a point is assigned for each factor that is present. Low risk patients (score=0) had a <15% risk of pain flare, intermediate risk patients (score=1) had a 15-20% risk, and high risk patients (score>1) had a 25-30% risk. | Kowalchuk, Pract Radiat Oncol 2022