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As opposed to melanoma or Merkel cell carcinoma, satellitosis is not taken into account when staging cutaneous squamous cell carcinoma (cSCC). Here is a retrospective look at outcomes among patients treated for cSCC at Cleveland Clinic of Brigham and Women’s Hospital with one of the following high risk features: T3 (n=341), T4 (n=36), N1-3 (n=70)., or presence of satellitosis (n=72). It turns out recurrence rates were significantly lower even among those with T3 (HR 0.21) and T4 (HR 0.36) disease than among those with satellitosis. When comparing disease-specific survival at 5 years, those with satellitosis fared significantly worse (41%) than those with T3 (76%) or T4 (64%) disease and similar to those with N1-3 (39%) disease. | Smile, JAMA Dermatol 2022


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