Pregnant with meaning.
This systematic review and meta-analysis of 39 studies of pregnancy after breast cancer found that survivors were less likely to become pregnant than the general population. Granted, the study can’t account for differences in the desire to become pregnant. Among those who did become pregnant, risks of C-section, low birth weight, and preterm birth were higher than the general population, especially if they received chemo. However, there was no increased risk of congenital abnormalities. Last, pregnancy had no detrimental survival effects. In fact, women who became pregnant actually had longer survival than survivors who did not, perhaps with post-treat fertility being a surrogate for good health. Another reason to opt for ovarian suppression in the treatment algorithm for premenopausal women with breast cancer? | Lambertini, J Clin Oncol 2021