Oh snap, Pap.
Cervical cancer screening just got a whole lot easier. Borne from large phase 3 data, HPV testing alone as infrequently as every 5 years and not beginning until age 25 is now the recommendation of the American Cancer Society. The success of HPV-vaccinations have proven the downfall of the traditional Pap smear—which, granted, served us well for nearly a century—given the pre-test probability of morphologically abnormal cervical cells representing cancer is now rock-bottom, along with the specificity of Pap smear alone. | Fantham, ACS 2020