Astros at ASTRO.

Retrospective testing (LBA 4) of tissue samples from 116 enrollees in RTOG 9813, which randomized patients receiving radiation for grade 3 astrocytomas to concurrent temozolomide or nitrosourea, reveals 55% are IDH1/2 mutant and 54% MGMT methylated with the characteristic most strongly influencing survival regardless of treatment being IDH1/2-status. | Fleming, ASTRO 2020


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