Looking for a CRISPR sound?

A remarkable study reports proof of concept that in vivo CRISPR technology can be used to ameliorate hereditary hearing loss resulting from a dominant allele point mutation that hinders appropriate development of cochlear hair cells in mice. A specially designed RNA guides a CRISPR-Cas9 complex to the mutant (but not wildtype) allele to slice and dice it and then let normal cellular DNA repair takeover. Anyone else hear this and think CRISPR-BRCA therapy..? | Gao, Nature 2018


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