Sarcoma metastatic to spine.

June 27, 2017. We’ve got a high biologically-equivalent dose (BED) treatment for that. A report published this week in JNS describes outcomes with spine stereotactic body radiosurgery (SBRT) for sarcoma mets. Unfortunately, there was a wide range of doses and fractionation schemes used, with over half receiving more than one fraction. Good news: One year local control was 81%. Bad news: Most failures occurred in the epidural space--a frequent site of failure with any spine SBRT. BED > 48 Gy and single vertebral body involvement were associated with better local control. The authors conclude ≥ 22 Gy in a single fraction achieves optimal control. Beam on.


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